Endocrine Abstracts

Introduction: Vitamin D has a potentially beneficial role in insulin resistance, but there is a lack of evidence in elderly. We report preliminary results of an ongoing study that investigated the effect vitamin D replacement treatment (12 weeks) on insulin resistance and metabolic parameters in elderly people with normal glucose tolerance.Methods/design: The study’s eligibility criteria were body mass index <30.0 kg/m2, creatinine le...

Objective: Diabetes mellitus (DM) is a complex disease that affects many systems. The most important cells of the immune system are lymphomononuclear (LMN) cells. Here, we aimed to evaluate the energy metabolism of LMN cells in patients with diabetes and impaired glucose tolerance.Methods: We measured LMN cell energy metabolism in patients with type 2 diabetes mellitus, impaired glucose tolerance (IGT) and healthy subjects. Cells were freshly isolated fr...